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Epidural stimulation leads to recovery of cardiovascular function in spinal-cord-injured posted Tuesday, 18 September 2018
For the first time since 2009, Stefanie Putnam is able to prepare -- and eat -- meals for herself, put the vest on her service dog, Kaz, and drive herself to activities with her horse without losing consciousness or gasping for breath. "My whole life has opened up for me again!" Putnam said. A C4 spinal cord injury in 2009 left Putnam paralyzed from the neck down and suffering from chronic low blood pressure. She relied on medication and tight corsets to maintain her blood pressure, but she still passed out five or six times a day...
Category: Clinical Trials


New Method to Create Human Neural Stem Cells Can Regenerate Spine in Rats, Study Shows posted Tuesday, 18 September 2018
Human spinal cord neural stem cells (NSC), created using an innovative method, were seen to regenerate functional neurons in the damaged tissue of rats with spinal injuries, according to researchers. Their study, “Generation and post-injury integration of human spinal cord neural stem cells,” was published in the journal Nature Methods. Spinal cord NSC were already known to have great potential to regenerate damaged spinal cords and re-establish the neural circuitry. However, these cells had never been created in the lab (in vitro)…
Category: Clinical Trials


University of Minnesota Researchers Develop 3D Printed Device to Treat Spinal Cord Injuries posted Wednesday, 15 August 2018
In the United States, 285,000 people are currently suffering from spinal cord injuries. Around 17,000 new spinal cord injuries are recorded every year. However, there are no good or precise treatments to help patients regain functions or alleviate pain. This could change, however, following the outline of research recently published in scientific journal Advanced Functional Materials. A collaboration between engineers and medical researchers from the University of Minnesota has resulted in a 3D printed device which may alleviate pain and help regain functions of muscles, bowels and bladder for patients with long-term spinal cord injuries…
Category: Clinical Trials


Created Line of Spinal Cord Neural Stem Cells Shows Diverse Promise posted Tuesday, 14 August 2018
Researchers at University of California San Diego School of Medicine report that they have successfully created spinal cord neural stem cells (NSCs) from human pluripotent stem cells (hPSCs) that differentiate into a diverse population of cells capable of dispersing throughout the spinal cord and can be maintained for long periods of time...
Category: Clinical Trials


New study offers hope of recovery from spinal cord injury posted Monday, 13 August 2018
Spinal cord injury or damage causes permanent changes in strength, sensation and other body functions. Hope of recuperation is slim to none. Now a new Tel Aviv University study finds the intravenous injection of a potent enzyme, just hours after an accident, has the potential to diminish a cascade of pathological events responsible for neuronal death, such as inflammation and scarring...
Category: Clinical Trials


BioArctic Receives Regulatory Approval in Finland for a Clinical Study in Patients With Complete Spinal Cord Injury posted Thursday, 12 July 2018
STOCKHOLM, July 10, 2018 /PRNewswire/ -- BioArctic AB (publ) (Nasdaq Stockholm: BIOA B) announced today that the company has received approval by Fimea, the Finnish Medicines Agency, and Valvira, the Finnish authority for medical device, as well as the local ethics committee for inclusion of Finnish patients in BioArctic's ongoing clinical Phase 1/2 study with SC0806. The candidate product is a combination of a medical device (implant) and a medicinal product (FGF1) for patients with complete spinal cord injury. This approval means that BioArctic has received approvals in all the countries planned to participate in the study, i.e. Sweden, Estonia, Norway and now Finland...
Category: Clinical Trials


Researchers repair acute spinal cord injury in monkeys posted Wednesday, 06 June 2018
Spinal cord injuries are among the most severe and difficult-to-treat medical conditions, usually resulting in permanent disability including loss of muscle function, sensation and autonomic functions. Medical research is now on the cusp of treating severe spinal cord injuries by inducing the repair of spinal nerves, and scientists have made strides in recent years with rodents and primates...
Category: Clinical Trials


In a Break with Dogma, Myelin Boosts Neuron Growth in Spinal Cord Injuries posted Friday, 25 May 2018
Recovery after severe spinal cord injury is notoriously fraught, with permanent paralysis often the result. In recent years, researchers have increasingly turned to stem cell-based therapies as a potential method for repairing and replacing damaged nerve cells. They have struggled, however, to overcome numerous innate barriers, including myelin, a mixture of insulating proteins and lipids that helps speed impulses through adult nerve fibers but also inhibits neuronal growth...
Category: Clinical Trials


UCLA researchers improve hand, arm mobility in paralysis patients posted Wednesday, 16 May 2018
UCLA researchers have partially restored hand and arm function in paralysis patients without performing surgery. In a study published in April, UCLA neuroscientists demonstrated a new technique to improve motor function in patients with severe spinal cord injuries. The researchers stimulated the spinal cord with electricity to help paralysis patients regain control over their hands and arms. Since the therapy is noninvasive, the researchers suggest their method may be easier to use and more affordable than other treatments, such as surgery…
Category: Clinical Trials


Noninvasive spinal stimulation method enables paralyzed people to regain use of hands, study finds posted Saturday, 28 April 2018
The ability to perform simple daily tasks can make a big difference in people's lives, especially for those with spinal cord injuries. A UCLA-led team of scientists reports that six people with severe spinal cord injuries—three of them completely paralyzed—have regained use of their hands and fingers for the first time in years after undergoing a nonsurgical, noninvasive spinal stimulation procedure the researchers developed...
Category: Clinical Trials

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