http://www.ejbjs.org/cgi/content/abstract/88/11/2400
By Alexandre Rasouli et.al., 2006 (The Journal of Bone and Joint Surgery)- Background: Recovery after injury to the peripheral nervous system is based on the pro-regenerative relationship between axons and the extracellular matrix, a relationship established by Schwann cells. As mechanical conditioning of Schwann cells has been shown to stimulate their regenerative behavior, we sought to determine whether transplantation of these cells to the central nervous system (i.e., the spinal cord), with its limited regenerative capacity after injury, would improve axonal regeneration and functional recovery…